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Health-related quality of life in patients with generalized pustular psoriasis – a Swedish register study

Norlin J, Löfvendahl S, Schmitt-Egenolf M

A new study from IHE, published in Annals of Medicine, reports health-related quality of life (HRQoL) in persons with generalized pustular psoriasis (GPP). GPP is a severe form of psoriasis, characterized by the presence of sterile pustules over the body. Using data from the Swedish National Register for Systemic Treatment of Psoriasis (PsoReg), researchers at IHE have investigated the HRQoL of life among persons with GPP compared to those with the more common type of psoriasis, plaque psoriasis. In PsoReg, 80 persons with GPP, of which 15 (19%) also had concomitant plaque psoriasis, and 7041 persons with plaque psoriasis only were identified. The study shows significantly decreased HRQoL, measured by two different HRQoL instruments (EuroQol-5 Dimensions [EQ-5D] and Dermatology Life Quality Index [DLQI]), in GPP compared with plaque psoriasis. The results, which are in line with international studies, highlight a need for more efficient healthcare interventions for this multisystem disease.
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Annals of Medicine, 2024; 56(1): 2341252
DOI: 10.1080/07853890.2024.2341252