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Cost-effectiveness of Maintenance Treatment with a Barrier-strengthe­ning Moisturizing Cream in Patients with Atopic Dermatitis in Finland, Norway and Sweden

Norrlid H, Hjalte F, Lundqvist A, Svensson Å & Ragnarson Tennvall G

Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries. Effective maintenance therapy during symptom-free episodes may prolong the time to eczema relapse according to a previously published clinical trial. The present study evaluates the cost-effectiveness of a barrier-strengthening moisturizer containing 5% urea, compared with a moisturizer with no active ingredients during eczema-free periods. A health economic microsimulation model, based on efficacy data from a randomized clinical trial, analysed the cost-effectiveness of the barrier-strengthening treatment in Finland, Norway and Sweden. The barrier-strengthening moisturizer was cost-saving compared with the moisturizer with no active ingredients in all 3 countries. The result was confirmed in all but one sensitivity analysis. In conclusion, the barrier-strengthening moisturizer is cost-effective as maintenance therapy for patients with atopic dermatitis compared with a moisturizer with no active ingredients.

Acta Derm Venereol 2016; 96: 173–176
DOI: 10.2340/00015555-2221